Past Seminars

Here is the list of our past seminars:


Marina Elez (LJP, UPMC, Paris). Biophysics seminar ENS-ESPCI. - Clement Nizak, Olivia Du Roure

Mutation dynamics and fitness effects followed in single cells

Mutations have been investigated for more than a century but never witnessed in action in single cells, thus preventing direct characterization of their dynamics and reliable estimation of the distribution of their fitness effects. Such estimates have wide application and are critical for most evolutionary models/studies. We accomplished this in Escherichia coli by employing microfluidics, time-lapse imaging, and by visualizing mutations in single cells by using a fluorescent tag of the Mismatch Repair System. I will present our results obtained for strains having a wide range of mutation rates and growing under controlled condition in the absence of exogenous stress.






Recent seminars  (0)


Marina Elez (LJP, UPMC, Paris). Biophysics seminar ENS-ESPCI. - Clement Nizak, Olivia Du Roure

Mutation dynamics and fitness effects followed in single cells

Mutations have been investigated for more than a century but never witnessed in action in single cells, thus preventing direct characterization of their dynamics and reliable estimation of the distribution of their fitness effects. Such estimates have wide application and are critical for most evolutionary models/studies. We accomplished this in Escherichia coli by employing microfluidics, time-lapse imaging, and by visualizing mutations in single cells by using a fluorescent tag of the Mismatch Repair System. I will present our results obtained for strains having a wide range of mutation rates and growing under controlled condition in the absence of exogenous stress.






Seminar archive  (219)


Top



See also...

Register our newsletter

Justo grâvida vel facîlisis çurcus porta non dapidûs c’est dictumst sét vel pulvîar vulputate orci sét litoré, aliquet classé lacus facîlisis pérès £at (...) 

> More...

Unregister our newsletter

Gravida potentié lobortïs odio pharetra diam dui nullä leçtus fames malesuada pésuéré, ut quam egestas égét à nunc mi ïpsum pulvinar mauris id, vel (...) 

> More...