Here is the list of our past seminars:
Rachid Thiam (LPS, ENS, Paris). ENS-ESPCI Biophysics Seminar - Rachid Thiam (LPS, ENS, PARIS)
Biogenesis mechanism of fat storage organelles
All organisms are able to store excess energy in order to buffer energy fluctuations. Excess energy is stored in the form of neutral lipids, i.e. fat, encapsulated in organelles called lipid droplets. These droplets are at the core of cellular lipid and energy metabolism. The regulation of lipid droplets, which starts form their formation to reuse, is critical to human health ; its impairment is indeed associated to many metabolic disorders including type II diabetes, liver steatosis, neurodegenerative and cardiac diseases. The list of lipid droplet identified functions has recently largely expanded and includes, for example, various non-metabolic functions such as in viral infections or cancers. Despite these multiple implications, how lipid droplets mechanistically form remains poorly understood. Under energy rich conditions, excess nutrients are transformed into neutral lipids that are synthesized within the inter-monolayer space of the endoplasmic reticulum. The lipids next gather to form a spherically budded droplet. How this droplet budding process exactly happens is unknown. This is one of the most important questions to address for better knowing the regulation and function of lipid droplets in the cell. My talk will present our recent progress to answer this question through a combination of physical and biological approaches.
Recent seminars (0)
Rachid Thiam (LPS, ENS, Paris). ENS-ESPCI Biophysics Seminar - Rachid Thiam (LPS, ENS, PARIS)
Biogenesis mechanism of fat storage organelles
All organisms are able to store excess energy in order to buffer energy fluctuations. Excess energy is stored in the form of neutral lipids, i.e. fat, encapsulated in organelles called lipid droplets. These droplets are at the core of cellular lipid and energy metabolism. The regulation of lipid droplets, which starts form their formation to reuse, is critical to human health ; its impairment is indeed associated to many metabolic disorders including type II diabetes, liver steatosis, neurodegenerative and cardiac diseases. The list of lipid droplet identified functions has recently largely expanded and includes, for example, various non-metabolic functions such as in viral infections or cancers. Despite these multiple implications, how lipid droplets mechanistically form remains poorly understood. Under energy rich conditions, excess nutrients are transformed into neutral lipids that are synthesized within the inter-monolayer space of the endoplasmic reticulum. The lipids next gather to form a spherically budded droplet. How this droplet budding process exactly happens is unknown. This is one of the most important questions to address for better knowing the regulation and function of lipid droplets in the cell. My talk will present our recent progress to answer this question through a combination of physical and biological approaches.
Seminar archive (275)
2018
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Victor Yashunsky (PCC, Institut Curie, Paris). ESPCI-ENS Biophysics seminar
Friday 15 June 2018 from 13:00 to 14:00 - ENS Conf IV, 2nd floor
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Victor Yashunsky (PCC, Institut Curie, Paris). ESPCI-ENS Biophysics seminar
Friday 15 June 2018 from 13:00 to 14:00 - ENS Conf IV, 2nd floor
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Julien Heuvingh (PMMH, ESPCI). ESPCI-ENS biophysics seminar
Friday 1 June 13:00-14:00 - A1 (Urbain)
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Julien Heuvingh (PMMH, ESPCI). ESPCI-ENS biophysics seminar
Friday 1 June 2018 from 13:00 to 14:00 - A1 (Urbain)
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Julien Heuvingh (PMMH, ESPCI). ESPCI-ENS biophysics seminar
Friday 1 June 2018 from 13:00 to 14:00 - A1 (Urbain)
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Will Ratcliff (Georgia Tech). Biophysics seminar ESPCI-ENS
Friday 18 May 2018 from 13:00 to 14:00 - ESPCI, Amphi Urbain ground Floor
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Will Ratcliff (Georgia Tech). Biophysics seminar ESPCI-ENS
Friday 18 May 2018 from 13:00 to 14:00 - ESPCI, Amphi Urbain ground Floor
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Arup K. Chakraborty (MIT, USA). Biophysics seminar ESPCI-ENS
From 11 May at 13:00 to 18 May 2018 at 14:00 - ENS Conf IV (24 rue Lhomond, 2nd floor)
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Arup K. Chakraborty (MIT, USA). Biophysics seminar ESPCI-ENS
From 11 May at 13:00 to 18 May 2018 at 14:00 - ENS Conf IV (24 rue Lhomond, 2nd floor)
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Thomas Gregor (Institut Pasteur). Biophysics Seminar ESPCI-ENS
Friday 4 May 13:00-14:00 - A1 (Urbain)
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Thomas Gregor (Institut Pasteur). Biophysics Seminar ESPCI-ENS
Friday 4 May 2018 from 13:00 to 14:00 - A1 (Urbain)
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Thomas Gregor (Institut Pasteur). Biophysics Seminar ESPCI-ENS
Friday 4 May 2018 from 13:00 to 14:00 - A1 (Urbain)
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Horacio Lopez Menendez. Biophysics seminar ESPCI-ENS
Friday 20 April 2018 from 13:00 to 14:00 - A1 (Urbain)
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Horacio Lopez Menendez. Biophysics seminar ESPCI-ENS
Friday 20 April 2018 from 13:00 to 14:00 - A1 (Urbain)
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Julien Dumont (Institut Jacques Monod). Biophysics seminar ESPCI-ENS
Friday 13 April 2018 from 13:00 to 14:00 - Conf IV, École Normale Supérieure,
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Julien Dumont (Institut Jacques Monod). Biophysics seminar ESPCI-ENS
Friday 13 April 2018 from 13:00 to 14:00 - Conf IV, École Normale Supérieure,
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Antoine Coulon (Institut Curie, Paris). Biophysics seminar ESPCI-ENS
Friday 6 April 2018 from 13:00 to 14:00 - Conf IV, Ecole Normale Supérieure
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Antoine Coulon (Institut Curie, Paris). Biophysics seminar ESPCI-ENS
Friday 6 April 2018 from 13:00 to 14:00 - Conf IV, Ecole Normale Supérieure
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Marina Garcia-Jove Navarro (Dept of Chemistry, ENS, Paris). Biophysics Seminar ESPCI-ENS
Friday 30 March 13:00-14:00 - ENS, Conf IV, 2nd floor
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Marina Garcia-Jove Navarro (Dept of Chemistry, ENS, Paris). Biophysics Seminar ESPCI-ENS
Friday 30 March 2018 from 13:00 to 14:00 - ENS, Conf IV, 2nd floor
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Marina Garcia-Jove Navarro (Dept of Chemistry, ENS, Paris). Biophysics Seminar ESPCI-ENS
Friday 30 March 2018 from 13:00 to 14:00 - ENS, Conf IV, 2nd floor
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Guillaume Dumenil (Institut Pasteur). Biophysics Seminar ESPCI-ENS
Friday 23 March 13:00-14:00 - A1 (Urbain)
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Guillaume Dumenil (Institut Pasteur, Paris). Biophysics Seminar ESPCI-ENS
Friday 23 March 2018 from 13:00 to 14:00 - Amphi Urbain, Ground Floor, Staircase N
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Guillaume Dumenil (Institut Pasteur). Biophysics Seminar ESPCI-ENS
Friday 23 March 2018 from 13:00 to 14:00 - A1 (Urbain)
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Guillaume Dumenil (Institut Pasteur, Paris). Biophysics Seminar ESPCI-ENS
Friday 23 March 2018 from 13:00 to 14:00 - Amphi Urbain, Ground Floor, Staircase N
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Guillaume Dumenil (Institut Pasteur). Biophysics Seminar ESPCI-ENS
Friday 23 March 2018 from 13:00 to 14:00 - A1 (Urbain)
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Nicolas Minc (Institut Jacques Monod). Biophysics seminar ESPCI-ENS
Friday 16 March 2018 from 13:00 to 14:00 - ENS, Conf IV, 2nd floor
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Nicolas Minc (Institut Jacques Monod). Biophysics seminar ESPCI-ENS
Friday 16 March 2018 from 13:00 to 14:00 - ENS, Conf IV, 2nd floor
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Dmitri Petrov (Stanford). Biophysics seminar ENS-ESPCI
Friday 9 March 2018 from 13:00 to 14:00 - A1 (Urbain)
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Dmitri Petrov (Stanford). Biophysics seminar ENS-ESPCI
Friday 9 March 2018 from 13:00 to 14:00 - A1 (Urbain)
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Arnaud Gautier (laboratoire PASTEUR, ENS, Paris). Biophysics Seminar ENS-ESPCI
Friday 2 March 2018 from 13:00 to 14:00 - ENS, Conf IV, 2nd floor
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Arnaud Gautier (laboratoire PASTEUR, ENS, Paris). Biophysics Seminar ENS-ESPCI
Friday 2 March 2018 from 13:00 to 14:00 - ENS, Conf IV, 2nd floor
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Paolo Pierobon (Institut Curie, Paris).Biophysics Seminar ESPCI-ENS
Friday 16 February 2018 from 13:00 to 14:00 - ENS, Conf IV, 2nd floor
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Paolo Pierobon (Institut Curie, Paris).Biophysics Seminar ESPCI-ENS
Friday 16 February 2018 from 13:00 to 14:00 - ENS, Conf IV, 2nd floor
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Emmanuel Beaurepaire (LOB, Polytechnique). Biophysics Seminar ESPCI-ENS
Friday 9 February 13:00-14:00 - Amphi Urbain, Ground Floor, Staircase N
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Emmanuel Beaurepaire (Lab for optics and biosciences, Ecole Polytechnique). Biophysics Seminar ESPCI-ENS
Friday 9 February 2018 from 13:00 to 14:00 - Amphi Urbain, Ground Floor, Staircase N
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Emmanuel Beaurepaire (Lab for optics and biosciences, Ecole Polytechnique). Biophysics Seminar ESPCI-ENS
Friday 9 February 2018 from 13:00 to 14:00 - Amphi Urbain, Ground Floor, Staircase N
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Michael Shelley (NYU and Flatiron Institute). Biophysics seminar ENS-ESPCI
Tuesday 16 January 11:00-12:00 - Amphi Joliot, 3rd Floor, Staircase N
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Michael Shelley (NYU and Flatiron Institute). Biophysics seminar ENS-ESPCI
Tuesday 16 January 2018 from 11:00 to 12:00 - Amphi Joliot, 3rd Floor, Staircase N
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Michael Shelley (NYU and Flatiron Institute). Biophysics seminar ENS-ESPCI
Tuesday 16 January 2018 from 11:00 to 12:00 - Amphi Joliot, 3rd Floor, Staircase N
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Marc Lefranc (Laboratoire PhLAM, Université de Lille). Biophysics seminar ENS-ESPCI.
Friday 12 January 13:00-14:00 - Amphi Urbain, Ground Floor, Staircase N
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Marc Lefranc (Laboratoire PhLAM, Université de Lille). Biophysics seminar ENS-ESPCI.
Friday 12 January 2018 from 13:00 to 14:00 - Amphi Urbain, Ground Floor, Staircase N
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Marc Lefranc (Laboratoire PhLAM, Université de Lille). Biophysics seminar ENS-ESPCI.
Friday 12 January 2018 from 13:00 to 14:00 - Amphi Urbain, Ground Floor, Staircase N
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Victor Yashunsky (PCC, Institut Curie, Paris). ESPCI-ENS Biophysics seminar
2017
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Calin Guet (Systems and Synthetic Biology of Genetic Networks, IST Austria). Biophysics seminar ENS-ESPCI.
Friday 8 December 2017 from 13:00 to 14:00 - École Normale Supérieure L361
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Calin Guet (Systems and Synthetic Biology of Genetic Networks, IST Austria). Biophysics seminar ENS-ESPCI.
Friday 8 December 2017 from 13:00 to 14:00 - École Normale Supérieure L361
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Marina Elez (LJP, UPMC, Paris). Biophysics seminar ENS-ESPCI.
Friday 24 November 2017 from 13:00 to 14:00 - ENS, Conf IV, 2nd floor
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Marina Elez (LJP, UPMC, Paris). Biophysics seminar ENS-ESPCI.
Friday 24 November 2017 from 13:00 to 14:00 - ENS, Conf IV, 2nd floor
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Hervé Isambert (PCC, Institut Curie, Paris). Biophysics Seminar ENS-ESPCI
Friday 17 November 2017 from 13:00 to 14:00 - Amphi Urbain, Ground Floor, Staircase N
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Hervé Isambert (PCC, Institut Curie, Paris). Biophysics Seminar ENS-ESPCI
Friday 17 November 2017 from 13:00 to 14:00 - Amphi Urbain, Ground Floor, Staircase N
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Jonas Ranft (LPS, ENS, Paris). Biophysics Seminar ENS-ESPCI
Friday 20 October 2017 from 13:00 to 14:00 - ESPCI, Amphi Joliot, 2nd Floor, Staircase N
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Jonas Ranft (LPS, ENS, Paris). Biophysics Seminar ENS-ESPCI
Friday 20 October 2017 from 13:00 to 14:00 - ESPCI, Amphi Joliot, 2nd Floor, Staircase N
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Raphael Voituriez (LJP & LPTMC, UPMC, Paris). Biophysics seminar ENS-ESPCI.
Friday 13 October 2017 from 13:00 to 14:00 - ENS, Conf IV, 2nd floor
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Raphael Voituriez (LJP & LPTMC, UPMC, Paris). Biophysics seminar ENS-ESPCI.
Friday 13 October 2017 from 13:00 to 14:00 - ENS, Conf IV, 2nd floor
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Marie Emilie Terret (CIRB, Collège de France, Paris). Biophysics seminar ENS-ESPCI.
Friday 6 October 2017 from 13:00 to 14:00 - Amphi Schützenberger , ESPCI Paris
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Marie Emilie Terret (CIRB, Collège de France, Paris). Biophysics seminar ENS-ESPCI.
Friday 6 October 2017 from 13:00 to 14:00 - Amphi Schützenberger , ESPCI Paris
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Philippe Marcq (PCC, Institut Curie, Paris). Biophysics seminar ENS-ESPCI.
Friday 29 September 2017 from 13:00 to 14:00 - ENS, Conf IV, 2nd floor
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Philippe Marcq (PCC, Institut Curie, Paris). Biophysics seminar ENS-ESPCI.
Friday 29 September 2017 from 13:00 to 14:00 - ENS, Conf IV, 2nd floor
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Boris Guirao (IBDD, Institut Curie, Paris). Biophysics seminar ENS-ESPCI.
Vendredi 22 septembre 2017 de 13h00 à 14h00
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Boris Guirao (IBDD, Institut Curie, Paris). Biophysics seminar ENS-ESPCI.
Vendredi 22 septembre 2017 de 13h00 à 14h00
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Jasna Brujic (NYU, USA). Biophysics seminar ENS-ESPCI.
Friday 30 June 2017 from 13:00 to 14:00 - ESPCI, Amphi Holweck, Ground Floor, Staircase C
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Jasna Brujic (NYU, USA). Biophysics seminar ENS-ESPCI.
Friday 30 June 2017 from 13:00 to 14:00 - ESPCI, Amphi Holweck, Ground Floor, Staircase C
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Bill Russ (UTSW Dallas). Biophysics seminar ENS-ESPCI.
Friday 23 June 2017 from 13:00 to 14:00 - ENS, Room L374/L376, 3rd floor
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Bill Russ (UTSW Dallas). Biophysics seminar ENS-ESPCI.
Friday 23 June 2017 from 13:00 to 14:00 - ENS, Room L374/L376, 3rd floor
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Shelly Tzlil (Technnion, Israël). Biophysics seminar ENS-ESPCI.
Friday 16 June 2017 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Shelly Tzlil (Technnion, Israël). Biophysics seminar ENS-ESPCI.
Friday 16 June 2017 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Jean Baudry (LCMD, CBI, ESPCI). Biophysics seminar ENS-ESPCI.
Friday 9 June 2017 from 13:00 to 14:00 - ENS, Room L374/376, 3rd floor
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Jean Baudry (LCMD, CBI, ESPCI). Biophysics seminar ENS-ESPCI.
Friday 9 June 2017 from 13:00 to 14:00 - ENS, Room L374/376, 3rd floor
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Paolo Pierobon (Institut Curie, Paris). Biophysics seminar ENS-ESPCI.
Friday 2 June 2017 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Paolo Pierobon (Institut Curie, Paris). Biophysics seminar ENS-ESPCI.
Friday 2 June 2017 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Marion Segall (PMMH, ESPCI et Funevol, MVHN, Paris). Biophysics seminar ENS-ESPCI.
Friday 19 May 2017 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Marion Segall (PMMH, ESPCI et Funevol, MVHN, Paris). Biophysics seminar ENS-ESPCI.
Friday 19 May 2017 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Mathieu Morel (ENS, Dept Chimie). Biophysics seminar ENS-ESPCI.
Friday 28 April 2017 from 13:00 to 14:00 - ENS, Room L374/L376, 3rd floor
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Mathieu Morel (ENS, Dept Chimie). Biophysics seminar ENS-ESPCI.
Friday 28 April 2017 from 13:00 to 14:00 - ENS, Room L374/L376, 3rd floor
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François Robin (IPBS, UPMC, Paris). ENS-ESPCI Biophysics Seminar
Friday 21 April 2017 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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François Robin (IPBS, UPMC, Paris). ENS-ESPCI Biophysics Seminar
Friday 21 April 2017 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Volker Bormuth (LJP, UPMC). ENS-ESPCI Biophysics Seminar
Friday 31 March 2017 from 13:00 to 14:00 - ENS, Room L374/L376, 3rd floor
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Volker Bormuth (LJP, UPMC). ENS-ESPCI Biophysics Seminar
Friday 31 March 2017 from 13:00 to 14:00 - ENS, Room L374/L376, 3rd floor
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Cécile Sykes (Institut Curie,Paris). ENS-ESPCI Biophysics Seminar
Friday 17 March 2017 from 13:00 to 14:00 - ENS, Room L374/L376 3rd floor
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Cécile Sykes (Institut Curie,Paris). ENS-ESPCI Biophysics Seminar
Friday 17 March 2017 from 13:00 to 14:00 - ENS, Room L374/L376 3rd floor
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Romain Brette (Institut de la Vision, UPMC). ENS-ESPCI Biophysics Seminar
Friday 10 March 2017 from 13:00 to 14:00
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Romain Brette (Institut de la Vision, UPMC). ENS-ESPCI Biophysics Seminar
Friday 10 March 2017 from 13:00 to 14:00
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Patricia Davidson (Institut Curie, Paris). ENS-ESPCI Biophysics Seminar
Friday 24 February 2017 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Patricia Davidson (Institut Curie, Paris). ENS-ESPCI Biophysics Seminar
Friday 24 February 2017 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Gregory Batt (INRIA, Saclay). Biophysics seminar ESPCI-ENS.
Friday 10 February 2017 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Gregory Batt (INRIA, Saclay). Biophysics seminar ESPCI-ENS.
Friday 10 February 2017 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Rachid Thiam (LPS, ENS, Paris). ENS-ESPCI Biophysics Seminar
Vendredi 3 février 2017 de 13h00 à 14h00 - ENS, Room L363/L365, 3rd floor
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Juliette Azimzadeh (Institut Jacques Monod). Biophysics seminar ESPCI-ENS.
Friday 27 January 2017 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Juliette Azimzadeh (Institut Jacques Monod). Biophysics seminar ESPCI-ENS.
Friday 27 January 2017 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Anton Zadorin (ESPCI, Paris). Biophysics seminar ESPCI-ENS.
Friday 20 January 2017 from 13:00 to 14:00 - ENS, Room L369, 3rd floor
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Anton Zadorin (ESPCI, Paris). Biophysics seminar ESPCI-ENS.
Friday 20 January 2017 from 13:00 to 14:00 - ENS, Room L369, 3rd floor
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Quantitative biology on cells using microfluidic arrays. Charles Baroud (Polytechnique & Institut Pasteur). Biophysics Seminar ESPCI-ENS.
Friday 13 January 2017 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Quantitative biology on cells using microfluidic arrays. Charles Baroud (Polytechnique & Institut Pasteur). Biophysics Seminar ESPCI-ENS.
Friday 13 January 2017 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Calin Guet (Systems and Synthetic Biology of Genetic Networks, IST Austria). Biophysics seminar ENS-ESPCI.
2016
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Pierre-Yves Colin (UCL, UK). Biophysics seminar ESPCI-ENS.
Friday 16 December 2016 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Pierre-Yves Colin (UCL, UK). Biophysics seminar ESPCI-ENS.
Friday 16 December 2016 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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César Valencia-Gallardo (Collège de France). Biophysics seminar ESPCI-ENS.
Friday 9 December 2016 from 13:00 to 14:00 - ENS, Room L369, 3rd floor
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César Valencia-Gallardo (Collège de France). Biophysics seminar ESPCI-ENS.
Friday 9 December 2016 from 13:00 to 14:00 - ENS, Room L369, 3rd floor
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Serge Dmitrieff (EMBL). Biophysics Seminar ESPCI-ENS.
Friday 2 December 2016 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Serge Dmitrieff (EMBL). Biophysics Seminar ESPCI-ENS.
Friday 2 December 2016 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Francis Corson (LPS, ENS). Biophysics seminar ESPCI-ENS.
Friday 25 November 2016 from 13:00 to 14:00 - ENS, Room L369, 3rd floor
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Francis Corson (LPS, ENS). Biophysics seminar ESPCI-ENS.
Friday 25 November 2016 from 13:00 to 14:00 - ENS, Room L369, 3rd floor
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Amaury Lambert (Collège de France). Biophysics Seminar ESPCI-ENS
Friday 18 November 2016 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Amaury Lambert (Collège de France). Biophysics Seminar ESPCI-ENS
Friday 18 November 2016 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Jean Leon Maitre (GDB, Institut Curie). Biophysics Seminar ESPCI-ENS
Friday 4 November 2016 from 13:00 to 14:00 - Amphi Urbain, Ground Floor, Staircase N
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Jean Leon Maitre (GDB, Institut Curie). Biophysics Seminar ESPCI-ENS
Friday 4 November 2016 from 13:00 to 14:00 - Amphi Urbain, Ground Floor, Staircase N
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Andrea Perez-Villa (IMPMC, UPMC, Paris). Biophysics Seminar ESPCI-ENS
Friday 28 October 2016 from 13:00 to 14:00 - ENS, Room L369, 3rd floor
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Andrea Perez-Villa (IMPMC, UPMC, Paris). Biophysics Seminar ESPCI-ENS
Friday 28 October 2016 from 13:00 to 14:00 - ENS, Room L369, 3rd floor
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Nicholas Rossi (University of Vermont). Biophysics seminar ESPCI-ENS
Friday 14 October 2016 from 13:00 to 14:00 - ENS, Room L369, 3rd floor
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Nicholas Rossi (University of Vermont). Biophysics seminar ESPCI-ENS
Friday 14 October 2016 from 13:00 to 14:00 - ENS, Room L369, 3rd floor
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Armita Nourmohammad (Princeton University). Biophysics Seminar ESPCI-ENS.
Friday 7 October 2016 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Armita Nourmohammad (Princeton University). Biophysics Seminar ESPCI-ENS.
Friday 7 October 2016 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Anton Crombach (CIRB, College de France). Biophysics Seminar ESPCI-ENS.
Friday 30 September 2016 from 13:00 to 14:00 - ENS, Room L369 3rd floor
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Anton Crombach (CIRB, College de France). Biophysics Seminar ESPCI-ENS.
Friday 30 September 2016 from 13:00 to 14:00 - ENS, Room L369 3rd floor
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Maxime Deforet (Memorial Sloan Kettering Cancer Center, New York). Biophysics Seminar ESPCI-ENS.
Friday 23 September 2016 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Maxime Deforet (Memorial Sloan Kettering Cancer Center, New York). Biophysics Seminar ESPCI-ENS.
Friday 23 September 2016 from 13:00 to 14:00 - ESPCI, Amphi Urbain, Ground Floor, Staircase N
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Biophysics seminar : Edo Kussell (NYU)
Jeudi 9 juin 2016 de 14h00 à 15h00 - A1 (Urbain)
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Biophysics seminar : Edo Kussell (NYU)
Jeudi 9 juin 2016 de 14h00 à 15h00 - A1 (Urbain)
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Pierre-Yves Colin (UCL, UK). Biophysics seminar ESPCI-ENS.
2013
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Séminaire de Biophysique ENS-ESPCI. Olivier Tenaillon (Faculté de Médecine Xavier Bichat).
Vendredi 27 septembre 2013 de 12h30 à 14h30 - A1 (Urbain)
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Séminaire de Biophysique ENS-ESPCI. Olivier Tenaillon (Faculté de Médecine Xavier Bichat).
Vendredi 27 septembre 2013 de 12h30 à 14h30 - A1 (Urbain)
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Séminaire de Biophysique ENS-ESPCI. Olivier Tenaillon (Faculté de Médecine Xavier Bichat).
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Nacho Molina (IGBM, Strasbourg). ENS-ESPCI Biophysics Seminar
Title and abstract to be announced
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Raphael Voituriez (LJP & LPTMC, UPMC, Paris). Biophysics seminar ENS-ESPCI.
Title and abstract to be announced
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Marie Emilie Terret (CIRB, Collège de France, Paris). Biophysics seminar ENS-ESPCI.
Title and abstract to be announced
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Philippe Marcq (PCC, Institut Curie, Paris). Biophysics seminar ENS-ESPCI.
Title and abstract to be announced
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Boris Guirao (IBDD, Institut Curie, Paris). Biophysics seminar ENS-ESPCI.
Title and abstract to be announced
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Bill Russ (UTSW Dallas). Biophysics seminar ENS-ESPCI.
Evolutionary principles of enzyme design
The central properties of proteins – folding, biochemical activity, adaptive capacity – arise from a complex pattern of energetic interactions between amino acid residues. However, due to the subtlety of the structure-energy rel(...)
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Jasna Brujic (NYU, USA). Biophysics seminar ENS-ESPCI.
Mayonnaise Robots
Traditionally, assembly lines to build machines, from electronic circuits to motor vehicles, follow specific instruction manuals, followed by robots or people. On the other hand, in biology, organisms self-assemble spontaneously according to instructions encoded in their gen(...)
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Shelly Tzlil (Technnion, Israël). Biophysics seminar ENS-ESPCI.
Title and abstract to be announced
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Paolo Pierobon (Institut Curie, Paris). Biophysics seminar ENS-ESPCI.
Mechanics and force patterning at the immune synapse.
In order to establish an efficient immune response, hence to produce high affinity antibodies, B cell have to internalize the antigen presented on the surface of neighboring cells in the lymph node (typically follicular dendritic cells and(...)
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Marion Segall (PMMH, ESPCI et Funevol, MVHN, Paris). Biophysics seminar ENS-ESPCI.
Water as a driver of evolution: the example of aquatic snakes.
Animal-environment interactions are determinant in driving the evolution of phenotypic variation. Most aquatic animals have developed adaptations to overcome the physical constraints inherent to an aquatic lifestyle. The aim of th(...)
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Mathieu Morel (ENS, Dept Chimie). Biophysics seminar ENS-ESPCI.
Single-Cell Analysis of Cancer Targeting Circuits: Lessons from Cellular Heterogeneity for Circuit Optimization
Targeting malignant cells in a heterogeneous population is a major challenge. Synthetic circuits integrating gene expression markers can discriminate cancer cells autonomously and(...)
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Jean Baudry (LCMD, CBI, ESPCI). Biophysics seminar ENS-ESPCI.
High throughput single cells phenotyping for immune response monitoring.
There have been significant recent advances in the development of single cell analysis tools. If these methods are creating new opportunities in biology, they are workable mostly for dead cells: chara(...)
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Romain Brette (Institut de la Vision, UPMC). ENS-ESPCI Biophysics Seminar
Neuronal geometry and excitability
Most theoretical studies on neural excitability have dealt with either
isopotential membranes, for example the space-clamped squid axon, or
homogeneous axons. However, in most vertebrate neurons, action
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Cécile Sykes (Institut Curie,Paris). ENS-ESPCI Biophysics Seminar
Tension build-up in cells and in biomimetic systems
Cell tension plays a crucial role in many biological processes; in particular, acto-myosin cortical tension drives many events of cell fate, including cell division. The tension of a cell is defined by analogy with the surface tension of a l(...)
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Volker Bormuth (LJP, UPMC). ENS-ESPCI Biophysics Seminar
Whole-brain imaging during vestibular stimulation in zebrafish with a novel rotatable light-sheet microscope
Light-sheet microscopy allows cell resolved whole-brain calcium imaging at several brain scans per second in zebrafish larvae. Currently this technique is not compatible with dynamic (...)
-
François Robin (IPBS, UPMC, Paris). ENS-ESPCI Biophysics Seminar
Organizing embryonic contractility in space and time.
Actomyosin dynamics in morphogenesis, from tissue to single molecules
The mechanical properties of embryonic cells define the landscape that drives morphogenesis. These mechanical properties deri(...)
-
Patricia Davidson (Institut Curie, Paris). ENS-ESPCI Biophysics Seminar
LINC-ing the cell nucleus, mechanics and disease
The ability of cells to migrate through tissues and interstitial spaces is essential during development and tissue homeostasis, immune cell mobility, and in various human diseases. In particular, deformation of the nucleus a(...)
-
Rachid Thiam (LPS, ENS, Paris). ENS-ESPCI Biophysics Seminar
Biogenesis mechanism of fat storage organelles
All organisms are able to store excess energy in order to buffer energy fluctuations. Excess energy is stored in the form of neutral lipids, i.e. fat, encapsulated in organelles called lipid droplets. These droplets are at the core of cellular l(...)
-
Gregory Batt (INRIA, Saclay). Biophysics seminar ESPCI-ENS.
Balancing a genetic toggle switch by real-time control or periodic stimulations
The ability to routinely control complex genetic circuits in vivo and in real-time promises quantitative understanding of cellular processes of unprecedented precision, quality, and richness. W(...)
-
Juliette Azimzadeh (Institut Jacques Monod). Biophysics seminar ESPCI-ENS.
Identification of Conserved Centriole Components Controlling Centriole Rotational Polarity in Multiciliated Cells
Multiciliated cells form hundreds of motile cilia that beat in a coordinated fashion to generate a fluid flow or displace particles and cells. To generate a directional fluid flow(...)
-
Anton Zadorin (ESPCI, Paris). Biophysics seminar ESPCI-ENS.
Synthesis of a reaction-diffusion French flag pattern
A central question of morphogenesis is the unfolding of genetic information into successive steps of complexification of an initially relatively simple egg or a bud. Experiments show that very often cellular differentia(...)
-
Francis Corson (LPS, ENS). Biophysics seminar ESPCI-ENS.
Positional information and self-organization: how the fly lays out its sense organs
The emergence of spatial patterns in developing multicellular organisms relies on positional cues and cell-cell communication. Drosophila sensory organs have informed a paradigm where these(...)
-
César Valencia-Gallardo (Collège de France). Biophysics seminar ESPCI-ENS.
Title and abstract to be anounced
-
Pierre-Yves Colin (UCL, UK). Biophysics seminar ESPCI-ENS.
Title and abstract to be anounced
-
Serge Dmitrieff (EMBL). Biophysics Seminar ESPCI-ENS.
Balance of microtubule stiffness and cortical tension determines the size of blood cells with marginal band across species
The fast blood stream of animals is associated with large shear stresses. Consequently, blood cells have evolved a special morphology and internal architecture allowing t(...)
-
Quantitative biology on cells using microfluidic arrays. Charles Baroud (Polytechnique & Institut Pasteur). Biophysics Seminar ESPCI-ENS.
Quantitative measurements on single cells are typically performed through flow cytometry, which yields high throughput data but only at a single instant on individualised cells. This leaves many unmet needs, such as following cell fate in time, looking at interactions between cells, or relating the cell behavior wit(...)
-
Amaury Lambert (Collège de France). Biophysics Seminar ESPCI-ENS
Chromosome painting
This talk is about a simple mathematical model of neutral population genetics with recombination. We assume that at time 0, all individuals of a haploid population have their unique chromosome painted in a distinct color. Now at each birth event, the chromosome of the newb(...)
-
Anton Crombach (CIRB, College de France). Biophysics Seminar ESPCI-ENS.
Quantitative mechanisms explain system drift in the dipteran gap gene network
Dipterans (flies, midges, and mosquitoes) determine segmentation along their main body axis during the blastoderm stage of embryogenesis. In the initial phase of segmentation, maternal gr(...)
-
Maxime Deforet (Memorial Sloan Kettering Cancer Center, New York). Biophysics Seminar ESPCI-ENS.
Bacterial swarming, an experimental model for studying morphogenesis and evolution in expanding populations
Bacterial swarming is the ability to collectively spread across surfaces. In Pseudomonas aeruginosa, an opportunistic pathogen, swarming colonies exhibit str(...)
-
Jean Leon Maitre (GDB, Institut Curie). Biophysics Seminar ESPCI-ENS
Mechanics of blastocyst morphogenesis
During pre-implantation development, the mammalian embryos forms the blastocyst, the structure that will implant into the uterus. Consisting of an epithelium enveloping a fluid-filled cavity and the inner cell mass, the blastocyst is s(...)
-
Andrea Perez-Villa (IMPMC, UPMC, Paris). Biophysics Seminar ESPCI-ENS
Title and abstract to be announced
-
Nicholas Rossi (University of Vermont). Biophysics seminar ESPCI-ENS
How master regulators coordinate antibiotic resistance without sacrificing downstream specialization
Stress response networks frequently have a single upstream regulator that controls many downstream genes. However, the downstream targets are often diverse, therefore it remains unclear how th(...)
-
Armita Nourmohammad (Princeton University). Biophysics Seminar ESPCI-ENS.
Statistical Physics of molecular evolution: from gene regulation to immune system.
Molecular phenotypes, such as gene expression or protein binding affinities are important targets of natural selection, and are often subject to time-dependent pressure form the env(...)
-
Biophysics seminar : Edo Kussell (NYU)
Evolutionary phase transitions in random environments
Bacteria can use memory mechanisms to increase long term growth rates in rapidly changing environments. In this talk, I will discuss experiments that show the existence of phenotypic memory in E.coli during metabolic tr(...)
-
Séminaire de Biophysique ENS-ESPCI. Olivier Tenaillon (Faculté de Médecine Xavier Bichat).
"Mutational Landscape of Betalactamase TEM-1"
Adaptation proceeds through the selection of mutations. The distribution of mutant fitness effect and the forces shaping this distribution are therefore keys to predict the evolutionary fate of organisms and their constituents such as enzymes. Here, by producing a(...)
-
Emmanuel Beaurepaire (LOB, Polytechnique). Biophysics Seminar ESPCI-ENS
Friday, Feb 9th
Title and abstract to be announced
-
Mike Shelley (NYU and Flatiron Institute). Biophysics seminar ENS-ESPCI
Active Mechanics in the Cell
Many fundamental phenomena in eukaryotic cells — nuclear migration, spindle positioning, chromosome segregation — involve the interaction of (often transitory) mechanical structures with boundaries and fluids. I
will disc(...)
-
Marc Lefranc (Laboratoire PhLAM, Université de Lille). Biophysics seminar ENS-ESPCI.
Synchronization of circadian clocks to diurnal cycles: from microscopic algae in changing weather to meal timing.
To anticipate periodic changes due to the alternation of days and nights, most living organisms rely on biological oscillators which serve as clocks and orches(...)
-
Tom Shimitzu (AMOLF Institute, Amsterdam). Biophysics seminar ENS-ESPCI
Giant fluctuations in a bacterial signaling network revealed by FRET in single cells
January 26th, 1pm at ENS
I will describe recent single-cell FRET experiments on the bacterial chemotaxis network, a protein signaling circuit consisting of thousands of molecules, where we have discove(...)
-
Arnaud Gautier (laboratoire PASTEUR, ENS, Paris). Biophysics Seminar ENS-ESPCI
March, 2nd at ENS
Title and Abstract to be announced
-
Paolo Pierobon (Institut Curie, Paris).Biophysics Seminar ESPCI-ENS
February 16th 1 pm at ENS
Title and abstract to be announced
-
Tom Shimitzu (AMOLF Institute, Amsterdam). Biophysics seminar ENS-ESPCI
Giant fluctuations in a bacterial signaling network revealed by FRET in single cells
January 26th, 1pm at ENS
I will describe recent single-cell FRET experiments on the bacterial chemotaxis network, a protein signaling circuit consisting of thousands of molecules, where we have discove(...)
-
Nacho Molina (IGBM, Strasbourg). ENS-ESPCI Biophysics Seminar
Title and abstract to be announced
-
Victor Yashunsky (PCC, Institut Curie, Paris). ESPCI-ENS Biophysics seminar
Collective organization and dynamics of cell cultures
Cells exhibit rich repertoire of dynamical behaviors, which depend on cell phenotype and microenvironment. Collective dynamics is not just a product of many individually moving units. Instead, cells coordinate their movements and move as c(...)
-
Julien Heuvingh (PMMH, ESPCI). ESPCI-ENS biophysics seminar
What we learn about the dynamics of actin by growing it from
cylinders, stars and diamonds
Actin is a major component of biological cells and forms filaments
that constantly polymerize and depolymerize. This activity is used by
-
Arup K. Chakraborty (MIT, USA). Biophysics seminar ESPCI-ENS
How to hit HIV where it hurts
Vaccination has saved more lives than any other medical procedure. But, some pathogens have evolved which have defied successful vaccination using the empirical paradigms pioneered by Pasteur and Jenner. I will describe how bringing together theoretical/computati(...)
-
Will Ratcliff (Georgia Tech). Biophysics seminar ESPCI-ENS
A tale of two microbes: using biophysics to study the origin of multicellularity and resolve the dynamics of microbial warfare.
Abstract: In this talk, I'll present recent results from two different systems in our lab that highlight the critical role played by cell-scale biophysics in evoluti(...)
-
Julien Dumont (Institut Jacques Monod). Biophysics seminar ESPCI-ENS
Control of microtubule dynamics in early embryos to adapt spindle size
to cell volumeSuccessive cell divisions during embryonic cleavage create
increasingly smaller cells, so intracellular structures must adapt
their size to remain functional. Mitotic (...)
-
Antoine Coulon (Institut Curie, Paris). Biophysics seminar ESPCI-ENS
Probing the spatiotemporal kinetics of transcription at the single-RNA level
The synthesis of mature messenger RNA molecules from the DNA sequence of a gene is a central step in gene expression and is regulated at many levels (transcription initiation, elongation, splicing(...)
-
Horacio Lopez Menendez. Biophysics seminar ESPCI-ENS
Mechanical Instabilities and their role on apoptotic cell extrusion
The balance between cell division and live or apoptotic cell extrusion states the tissue homeostasis. It has strong implications in developmental processes such as morphogenesis and pathological processes(...)
-
Thomas Gregor (Institut Pasteur). Biophysics Seminar ESPCI-ENS
How the physics of enhancers shapes development
Enhancers are small regulatory pieces of DNA that control the activity
of genes, which eventually determine cellular fates during the
development of multicellular organisms. They need to (...)
-
Guillaume Dumenil (Institut Pasteur, Paris). Biophysics Seminar ESPCI-ENS
Mechanics of vascular colonization by Neisseria meningitidis
Bacterial infection of human vasculature can lead to unregulated
systemic activation of coagulation and innate immunity and rapidly
becomes life threatening. Neisseria mening(...)
-
Nicolas Minc (Institut Jacques Monod). Biophysics seminar ESPCI-ENS
Cell shape, microtubule asters and early embryonic development
Life for all animals starts with the fertilization of the egg, followed by the centration of the sperm nucleus and a 3D-choreography of reductive cell divisions called cleavage patterns. These invariant morphogenetic processes re(...)
-
Tom Shimitzu (AMOLF Institute, Amsterdam). Biophysics seminar ENS-ESPCI
Giant fluctuations in a bacterial signaling network revealed by FRET in single cells
January 26th, 1pm at ENS
I will describe recent single-cell FRET experiments on the bacterial chemotaxis network, a protein signaling circuit consisting of thousands of molecules, where we have discove(...)
-
Arnaud Gautier (laboratoire PASTEUR, ENS, Paris). Biophysics Seminar ENS-ESPCI
Inducible chemical-genetic fluorescent markers for bioimaging on-demand
Abstract: Deciphering the complex mechanisms controlling cells and organisms requires effective imaging systems and fluorescent probes to observe and quantify biomolecules in real time with high spatio(...)
-
Paolo Pierobon (Institut Curie, Paris).Biophysics Seminar ESPCI-ENS
Force patterning at the immune synapse.
In order to establish an efficient immune response, hence to produce high affinity antibodies, B cell have to internalize the antigen presented on the surface of neighboring cells in the lymph node (typically follicular dendritic cel(...)
-
Marina Garcia-Jove Navarro (Dept of Chemistry, ENS, Paris). Biophysics Seminar ESPCI-ENS
Building phase-separated RNA-protein compartments in mammalian cells to study membrane-less organelles
Membrane-less organelles are ubiquitous intracellular compartments that localize and regulate complex biological processes without being surrounded by a boundary structure. They have been de(...)
-
Emmanuel Beaurepaire (Lab for optics and biosciences, Ecole Polytechnique). Biophysics Seminar ESPCI-ENS
Nonlinear optical microscopy of developing and brain tissue
Modern issues in developmental biology and in neuroscience often require tissue-scale measurements of multiple cell parameters. Multiphoton fluorescence microscopy is a key technique for tissue studies with its ab(...)
-
Michael Shelley (NYU and Flatiron Institute). Biophysics seminar ENS-ESPCI
Active Mechanics in the Cell
Many fundamental phenomena in eukaryotic cells — nuclear migration, spindle positioning, chromosome segregation — involve the interaction of (often transitory) mechanical structures with boundaries and fluids. I
will disc(...)
-
Marc Lefranc (Laboratoire PhLAM, Université de Lille). Biophysics seminar ENS-ESPCI.
Synchronization of circadian clocks to diurnal cycles: from microscopic algae in changing weather to meal timing.
To anticipate periodic changes due to the alternation of days and nights, most living organisms rely on biological oscillators which serve as clocks and orches(...)
-
Guillaume Dumenil (Institut Pasteur). Biophysics Seminar ESPCI-ENS
Mechanics of vascular colonization by Neisseria meningitidis
Bacterial infection of human vasculature can lead to unregulated
systemic activation of coagulation and innate immunity and rapidly
becomes life threatening. Neisseria mening(...)
-
Dmitri Petrov (Stanford). Biophysics seminar ENS-ESPCI
Barcoding Rapid Evolution
Although evolutionary change is often assumed to be slow, many of the
key problems facing humanity are problems of extremely rapid evolution
taking place over years, months, or even days. Cancer, viral and
bact(...)
-
Hervé Isambert (PCC, Institut Curie, Paris). Biophysics Seminar ENS-ESPCI
Network reconstruction from multivariate information in genomic data
Network reconstruction has become ubiquitous to analyze the rapidly expanding, information-rich data of biological interest. However, most network learning methods are restricted to specific types of data(...)
-
Jonas Ranft (LPS, ENS, Paris). Biophysics Seminar ENS-ESPCI
Lifetime of a structure evolving by cluster aggregation and particle loss, and application to postsynaptic scaffold domains
The aggregation of proteins in the cell membrane plays an important role in the formation of mesoscopic biological structures such as E-cadherin clusters or postsynaptic(...)
-
Calin Guet (Systems and Synthetic Biology of Genetic Networks, IST Austria). Biophysics seminar ENS-ESPCI.
Title and abstract to be announced
-
Marina Elez (LJP, UPMC, Paris). Biophysics seminar ENS-ESPCI.
Mutation dynamics and fitness effects followed in single cells
Mutations have been investigated for more than a century but never witnessed in action in single cells, thus preventing direct characterization of their dynamics and reliable estimation of the distribution of t(...)
-
Raphael Voituriez (LJP & LPTMC, UPMC, Paris). Biophysics seminar ENS-ESPCI.
Actin flows in cell migration: from locomotion to trajectories
Eukaryotic cell movement is characterized by very diverse migration modes. Recent studies show that cells can adapt to environmental cues, such as adhesion and geometric confinement, thereby readily switching (...)
-
Marie Emilie Terret (CIRB, Collège de France, Paris). Biophysics seminar ENS-ESPCI.
Cortical tension participates in chromosome alignment in mouse oocytes.
In oocytes, cells lacking canonical centrosomes, two F-actin networks replace astral microtubules for spindle positioning. They exert forces on the spindle sufficient to embark it to the cortex, leading to an asymmetric division in size. (...)
-
Philippe Marcq (PCC, Institut Curie, Paris). Biophysics seminar ENS-ESPCI.
From cells to tissue: A continuum model of epithelial mechanics
A continuum model of epithelial tissue mechanics is formulated using
cellular-level mechanical ingredients and cell morphogenetic processes,
including cellular shape chang(...)
-
Boris Guirao (IBDD, Institut Curie, Paris). Biophysics seminar ENS-ESPCI.
From Cells to Tissues : Unified Characterization of Epithelial Tissue
Development
Understanding the mechanisms regulating development requires a quantitative characterization of cell divisions, rearrangements, cell size and shape changes, and apoptoses. (...)
-
Bill Russ (UTSW Dallas). Biophysics seminar ENS-ESPCI.
Evolutionary principles of enzyme design
The central properties of proteins – folding, biochemical activity, adaptive capacity – arise from a complex pattern of energetic interactions between amino acid residues. However, due to the subtlety of the structure-energy rel(...)
-
Jasna Brujic (NYU, USA). Biophysics seminar ENS-ESPCI.
Mayonnaise Robots
Traditionally, assembly lines to build machines, from electronic circuits to motor vehicles, follow specific instruction manuals, followed by robots or people. On the other hand, in biology, organisms self-assemble spontaneously according to instructions encoded in their gen(...)
-
Shelly Tzlil (Technnion, Israël). Biophysics seminar ENS-ESPCI.
Title and abstract to be announced
-
Paolo Pierobon (Institut Curie, Paris). Biophysics seminar ENS-ESPCI.
Mechanics and force patterning at the immune synapse.
In order to establish an efficient immune response, hence to produce high affinity antibodies, B cell have to internalize the antigen presented on the surface of neighboring cells in the lymph node (typically follicular dendritic cells and(...)
-
Marion Segall (PMMH, ESPCI et Funevol, MVHN, Paris). Biophysics seminar ENS-ESPCI.
Water as a driver of evolution: the example of aquatic snakes.
Animal-environment interactions are determinant in driving the evolution of phenotypic variation. Most aquatic animals have developed adaptations to overcome the physical constraints inherent to an aquatic lifestyle. The aim of th(...)
-
Mathieu Morel (ENS, Dept Chimie). Biophysics seminar ENS-ESPCI.
Single-Cell Analysis of Cancer Targeting Circuits: Lessons from Cellular Heterogeneity for Circuit Optimization
Targeting malignant cells in a heterogeneous population is a major challenge. Synthetic circuits integrating gene expression markers can discriminate cancer cells autonomously and(...)
-
Jean Baudry (LCMD, CBI, ESPCI). Biophysics seminar ENS-ESPCI.
High throughput single cells phenotyping for immune response monitoring.
There have been significant recent advances in the development of single cell analysis tools. If these methods are creating new opportunities in biology, they are workable mostly for dead cells: chara(...)
-
Romain Brette (Institut de la Vision, UPMC). ENS-ESPCI Biophysics Seminar
Neuronal geometry and excitability
Most theoretical studies on neural excitability have dealt with either
isopotential membranes, for example the space-clamped squid axon, or
homogeneous axons. However, in most vertebrate neurons, action
-
Cécile Sykes (Institut Curie,Paris). ENS-ESPCI Biophysics Seminar
Tension build-up in cells and in biomimetic systems
Cell tension plays a crucial role in many biological processes; in particular, acto-myosin cortical tension drives many events of cell fate, including cell division. The tension of a cell is defined by analogy with the surface tension of a l(...)
-
Volker Bormuth (LJP, UPMC). ENS-ESPCI Biophysics Seminar
Whole-brain imaging during vestibular stimulation in zebrafish with a novel rotatable light-sheet microscope
Light-sheet microscopy allows cell resolved whole-brain calcium imaging at several brain scans per second in zebrafish larvae. Currently this technique is not compatible with dynamic (...)
-
François Robin (IPBS, UPMC, Paris). ENS-ESPCI Biophysics Seminar
Organizing embryonic contractility in space and time.
Actomyosin dynamics in morphogenesis, from tissue to single molecules
The mechanical properties of embryonic cells define the landscape that drives morphogenesis. These mechanical properties deri(...)
-
Patricia Davidson (Institut Curie, Paris). ENS-ESPCI Biophysics Seminar
LINC-ing the cell nucleus, mechanics and disease
The ability of cells to migrate through tissues and interstitial spaces is essential during development and tissue homeostasis, immune cell mobility, and in various human diseases. In particular, deformation of the nucleus a(...)
-
Rachid Thiam (LPS, ENS, Paris). ENS-ESPCI Biophysics Seminar
Biogenesis mechanism of fat storage organelles
All organisms are able to store excess energy in order to buffer energy fluctuations. Excess energy is stored in the form of neutral lipids, i.e. fat, encapsulated in organelles called lipid droplets. These droplets are at the core of cellular l(...)
-
Nacho Molina (IGBM, Strasbourg). ENS-ESPCI Biophysics Seminar
Title and abstract to be announced
-
Gregory Batt (INRIA, Saclay). Biophysics seminar ESPCI-ENS.
Balancing a genetic toggle switch by real-time control or periodic stimulations
The ability to routinely control complex genetic circuits in vivo and in real-time promises quantitative understanding of cellular processes of unprecedented precision, quality, and richness. W(...)
-
Juliette Azimzadeh (Institut Jacques Monod). Biophysics seminar ESPCI-ENS.
Identification of Conserved Centriole Components Controlling Centriole Rotational Polarity in Multiciliated Cells
Multiciliated cells form hundreds of motile cilia that beat in a coordinated fashion to generate a fluid flow or displace particles and cells. To generate a directional fluid flow(...)
-
Anton Zadorin (ESPCI, Paris). Biophysics seminar ESPCI-ENS.
Synthesis of a reaction-diffusion French flag pattern
A central question of morphogenesis is the unfolding of genetic information into successive steps of complexification of an initially relatively simple egg or a bud. Experiments show that very often cellular differentia(...)
-
Francis Corson (LPS, ENS). Biophysics seminar ESPCI-ENS.
Positional information and self-organization: how the fly lays out its sense organs
The emergence of spatial patterns in developing multicellular organisms relies on positional cues and cell-cell communication. Drosophila sensory organs have informed a paradigm where these(...)
-
César Valencia-Gallardo (Collège de France). Biophysics seminar ESPCI-ENS.
Title and abstract to be anounced
-
Pierre-Yves Colin (UCL, UK). Biophysics seminar ESPCI-ENS.
Title and abstract to be anounced
-
Serge Dmitrieff (EMBL). Biophysics Seminar ESPCI-ENS.
Balance of microtubule stiffness and cortical tension determines the size of blood cells with marginal band across species
The fast blood stream of animals is associated with large shear stresses. Consequently, blood cells have evolved a special morphology and internal architecture allowing t(...)
-
Quantitative biology on cells using microfluidic arrays. Charles Baroud (Polytechnique & Institut Pasteur). Biophysics Seminar ESPCI-ENS.
Quantitative measurements on single cells are typically performed through flow cytometry, which yields high throughput data but only at a single instant on individualised cells. This leaves many unmet needs, such as following cell fate in time, looking at interactions between cells, or relating the cell behavior wit(...)
-
Amaury Lambert (Collège de France). Biophysics Seminar ESPCI-ENS
Chromosome painting
This talk is about a simple mathematical model of neutral population genetics with recombination. We assume that at time 0, all individuals of a haploid population have their unique chromosome painted in a distinct color. Now at each birth event, the chromosome of the newb(...)
-
Anton Crombach (CIRB, College de France). Biophysics Seminar ESPCI-ENS.
Quantitative mechanisms explain system drift in the dipteran gap gene network
Dipterans (flies, midges, and mosquitoes) determine segmentation along their main body axis during the blastoderm stage of embryogenesis. In the initial phase of segmentation, maternal gr(...)
-
Maxime Deforet (Memorial Sloan Kettering Cancer Center, New York). Biophysics Seminar ESPCI-ENS.
Bacterial swarming, an experimental model for studying morphogenesis and evolution in expanding populations
Bacterial swarming is the ability to collectively spread across surfaces. In Pseudomonas aeruginosa, an opportunistic pathogen, swarming colonies exhibit str(...)
-
Jean Leon Maitre (GDB, Institut Curie). Biophysics Seminar ESPCI-ENS
Mechanics of blastocyst morphogenesis
During pre-implantation development, the mammalian embryos forms the blastocyst, the structure that will implant into the uterus. Consisting of an epithelium enveloping a fluid-filled cavity and the inner cell mass, the blastocyst is s(...)
-
Andrea Perez-Villa (IMPMC, UPMC, Paris). Biophysics Seminar ESPCI-ENS
Title and abstract to be announced
-
Nicholas Rossi (University of Vermont). Biophysics seminar ESPCI-ENS
How master regulators coordinate antibiotic resistance without sacrificing downstream specialization
Stress response networks frequently have a single upstream regulator that controls many downstream genes. However, the downstream targets are often diverse, therefore it remains unclear how th(...)
-
Armita Nourmohammad (Princeton University). Biophysics Seminar ESPCI-ENS.
Statistical Physics of molecular evolution: from gene regulation to immune system.
Molecular phenotypes, such as gene expression or protein binding affinities are important targets of natural selection, and are often subject to time-dependent pressure form the env(...)
-
Biophysics seminar : Edo Kussell (NYU)
Evolutionary phase transitions in random environments
Bacteria can use memory mechanisms to increase long term growth rates in rapidly changing environments. In this talk, I will discuss experiments that show the existence of phenotypic memory in E.coli during metabolic tr(...)
-
Séminaire de Biophysique ENS-ESPCI. Olivier Tenaillon (Faculté de Médecine Xavier Bichat).
"Mutational Landscape of Betalactamase TEM-1"
Adaptation proceeds through the selection of mutations. The distribution of mutant fitness effect and the forces shaping this distribution are therefore keys to predict the evolutionary fate of organisms and their constituents such as enzymes. Here, by producing a(...)
-
Victor Yashunsky (PCC, Institut Curie, Paris). ESPCI-ENS Biophysics seminar
Collective organization and dynamics of cell cultures
Cells exhibit rich repertoire of dynamical behaviors, which depend on cell phenotype and microenvironment. Collective dynamics is not just a product of many individually moving units. Instead, cells coordinate their movements and move as c(...)
-
Julien Heuvingh (PMMH, ESPCI). ESPCI-ENS biophysics seminar
What we learn about the dynamics of actin by growing it from
cylinders, stars and diamonds
Actin is a major component of biological cells and forms filaments
that constantly polymerize and depolymerize. This activity is used by
-
Arup K. Chakraborty (MIT, USA). Biophysics seminar ESPCI-ENS
How to hit HIV where it hurts
Vaccination has saved more lives than any other medical procedure. But, some pathogens have evolved which have defied successful vaccination using the empirical paradigms pioneered by Pasteur and Jenner. I will describe how bringing together theoretical/computati(...)
-
Will Ratcliff (Georgia Tech). Biophysics seminar ESPCI-ENS
A tale of two microbes: using biophysics to study the origin of multicellularity and resolve the dynamics of microbial warfare.
Abstract: In this talk, I'll present recent results from two different systems in our lab that highlight the critical role played by cell-scale biophysics in evoluti(...)
-
Julien Dumont (Institut Jacques Monod). Biophysics seminar ESPCI-ENS
Control of microtubule dynamics in early embryos to adapt spindle size
to cell volumeSuccessive cell divisions during embryonic cleavage create
increasingly smaller cells, so intracellular structures must adapt
their size to remain functional. Mitotic (...)
-
Antoine Coulon (Institut Curie, Paris). Biophysics seminar ESPCI-ENS
Probing the spatiotemporal kinetics of transcription at the single-RNA level
The synthesis of mature messenger RNA molecules from the DNA sequence of a gene is a central step in gene expression and is regulated at many levels (transcription initiation, elongation, splicing(...)
-
Horacio Lopez Menendez. Biophysics seminar ESPCI-ENS
Mechanical Instabilities and their role on apoptotic cell extrusion
The balance between cell division and live or apoptotic cell extrusion states the tissue homeostasis. It has strong implications in developmental processes such as morphogenesis and pathological processes(...)
-
Thomas Gregor (Institut Pasteur). Biophysics Seminar ESPCI-ENS
How the physics of enhancers shapes development
Enhancers are small regulatory pieces of DNA that control the activity
of genes, which eventually determine cellular fates during the
development of multicellular organisms. They need to (...)
-
Guillaume Dumenil (Institut Pasteur, Paris). Biophysics Seminar ESPCI-ENS
Mechanics of vascular colonization by Neisseria meningitidis
Bacterial infection of human vasculature can lead to unregulated
systemic activation of coagulation and innate immunity and rapidly
becomes life threatening. Neisseria mening(...)
-
Nicolas Minc (Institut Jacques Monod). Biophysics seminar ESPCI-ENS
Cell shape, microtubule asters and early embryonic development
Life for all animals starts with the fertilization of the egg, followed by the centration of the sperm nucleus and a 3D-choreography of reductive cell divisions called cleavage patterns. These invariant morphogenetic processes re(...)
-
Arnaud Gautier (laboratoire PASTEUR, ENS, Paris). Biophysics Seminar ENS-ESPCI
Inducible chemical-genetic fluorescent markers for bioimaging on-demand
Abstract: Deciphering the complex mechanisms controlling cells and organisms requires effective imaging systems and fluorescent probes to observe and quantify biomolecules in real time with high spatio(...)
-
Paolo Pierobon (Institut Curie, Paris).Biophysics Seminar ESPCI-ENS
Force patterning at the immune synapse.
In order to establish an efficient immune response, hence to produce high affinity antibodies, B cell have to internalize the antigen presented on the surface of neighboring cells in the lymph node (typically follicular dendritic cel(...)
-
Marina Garcia-Jove Navarro (Dept of Chemistry, ENS, Paris). Biophysics Seminar ESPCI-ENS
Building phase-separated RNA-protein compartments in mammalian cells to study membrane-less organelles
Membrane-less organelles are ubiquitous intracellular compartments that localize and regulate complex biological processes without being surrounded by a boundary structure. They have been de(...)
-
Emmanuel Beaurepaire (Lab for optics and biosciences, Ecole Polytechnique). Biophysics Seminar ESPCI-ENS
Nonlinear optical microscopy of developing and brain tissue
Modern issues in developmental biology and in neuroscience often require tissue-scale measurements of multiple cell parameters. Multiphoton fluorescence microscopy is a key technique for tissue studies with its ab(...)
-
Michael Shelley (NYU and Flatiron Institute). Biophysics seminar ENS-ESPCI
Active Mechanics in the Cell
Many fundamental phenomena in eukaryotic cells — nuclear migration, spindle positioning, chromosome segregation — involve the interaction of (often transitory) mechanical structures with boundaries and fluids. I
will disc(...)
-
Marc Lefranc (Laboratoire PhLAM, Université de Lille). Biophysics seminar ENS-ESPCI.
Synchronization of circadian clocks to diurnal cycles: from microscopic algae in changing weather to meal timing.
To anticipate periodic changes due to the alternation of days and nights, most living organisms rely on biological oscillators which serve as clocks and orches(...)
-
Guillaume Dumenil (Institut Pasteur). Biophysics Seminar ESPCI-ENS
Mechanics of vascular colonization by Neisseria meningitidis
Bacterial infection of human vasculature can lead to unregulated
systemic activation of coagulation and innate immunity and rapidly
becomes life threatening. Neisseria mening(...)
-
Dmitri Petrov (Stanford). Biophysics seminar ENS-ESPCI
Barcoding Rapid Evolution
Although evolutionary change is often assumed to be slow, many of the
key problems facing humanity are problems of extremely rapid evolution
taking place over years, months, or even days. Cancer, viral and
bact(...)
-
Hervé Isambert (PCC, Institut Curie, Paris). Biophysics Seminar ENS-ESPCI
Network reconstruction from multivariate information in genomic data
Network reconstruction has become ubiquitous to analyze the rapidly expanding, information-rich data of biological interest. However, most network learning methods are restricted to specific types of data(...)
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Jonas Ranft (LPS, ENS, Paris). Biophysics Seminar ENS-ESPCI
Lifetime of a structure evolving by cluster aggregation and particle loss, and application to postsynaptic scaffold domains
The aggregation of proteins in the cell membrane plays an important role in the formation of mesoscopic biological structures such as E-cadherin clusters or postsynaptic(...)
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Calin Guet (Systems and Synthetic Biology of Genetic Networks, IST Austria). Biophysics seminar ENS-ESPCI.
Title and abstract to be announced
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Marina Elez (LJP, UPMC, Paris). Biophysics seminar ENS-ESPCI.
Mutation dynamics and fitness effects followed in single cells
Mutations have been investigated for more than a century but never witnessed in action in single cells, thus preventing direct characterization of their dynamics and reliable estimation of the distribution of t(...)
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Raphael Voituriez (LJP & LPTMC, UPMC, Paris). Biophysics seminar ENS-ESPCI.
Actin flows in cell migration: from locomotion to trajectories
Eukaryotic cell movement is characterized by very diverse migration modes. Recent studies show that cells can adapt to environmental cues, such as adhesion and geometric confinement, thereby readily switching (...)
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Marie Emilie Terret (CIRB, Collège de France, Paris). Biophysics seminar ENS-ESPCI.
Cortical tension participates in chromosome alignment in mouse oocytes.
In oocytes, cells lacking canonical centrosomes, two F-actin networks replace astral microtubules for spindle positioning. They exert forces on the spindle sufficient to embark it to the cortex, leading to an asymmetric division in size. (...)
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Philippe Marcq (PCC, Institut Curie, Paris). Biophysics seminar ENS-ESPCI.
From cells to tissue: A continuum model of epithelial mechanics
A continuum model of epithelial tissue mechanics is formulated using
cellular-level mechanical ingredients and cell morphogenetic processes,
including cellular shape chang(...)
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Boris Guirao (IBDD, Institut Curie, Paris). Biophysics seminar ENS-ESPCI.
From Cells to Tissues : Unified Characterization of Epithelial Tissue
Development
Understanding the mechanisms regulating development requires a quantitative characterization of cell divisions, rearrangements, cell size and shape changes, and apoptoses. (...)
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Bill Russ (UTSW Dallas). Biophysics seminar ENS-ESPCI.
Evolutionary principles of enzyme design
The central properties of proteins – folding, biochemical activity, adaptive capacity – arise from a complex pattern of energetic interactions between amino acid residues. However, due to the subtlety of the structure-energy rel(...)
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Jasna Brujic (NYU, USA). Biophysics seminar ENS-ESPCI.
Mayonnaise Robots
Traditionally, assembly lines to build machines, from electronic circuits to motor vehicles, follow specific instruction manuals, followed by robots or people. On the other hand, in biology, organisms self-assemble spontaneously according to instructions encoded in their gen(...)
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Shelly Tzlil (Technnion, Israël). Biophysics seminar ENS-ESPCI.
Title and abstract to be announced
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Paolo Pierobon (Institut Curie, Paris). Biophysics seminar ENS-ESPCI.
Mechanics and force patterning at the immune synapse.
In order to establish an efficient immune response, hence to produce high affinity antibodies, B cell have to internalize the antigen presented on the surface of neighboring cells in the lymph node (typically follicular dendritic cells and(...)
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Marion Segall (PMMH, ESPCI et Funevol, MVHN, Paris). Biophysics seminar ENS-ESPCI.
Water as a driver of evolution: the example of aquatic snakes.
Animal-environment interactions are determinant in driving the evolution of phenotypic variation. Most aquatic animals have developed adaptations to overcome the physical constraints inherent to an aquatic lifestyle. The aim of th(...)
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Mathieu Morel (ENS, Dept Chimie). Biophysics seminar ENS-ESPCI.
Single-Cell Analysis of Cancer Targeting Circuits: Lessons from Cellular Heterogeneity for Circuit Optimization
Targeting malignant cells in a heterogeneous population is a major challenge. Synthetic circuits integrating gene expression markers can discriminate cancer cells autonomously and(...)
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Jean Baudry (LCMD, CBI, ESPCI). Biophysics seminar ENS-ESPCI.
High throughput single cells phenotyping for immune response monitoring.
There have been significant recent advances in the development of single cell analysis tools. If these methods are creating new opportunities in biology, they are workable mostly for dead cells: chara(...)
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Romain Brette (Institut de la Vision, UPMC). ENS-ESPCI Biophysics Seminar
Neuronal geometry and excitability
Most theoretical studies on neural excitability have dealt with either
isopotential membranes, for example the space-clamped squid axon, or
homogeneous axons. However, in most vertebrate neurons, action
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Cécile Sykes (Institut Curie,Paris). ENS-ESPCI Biophysics Seminar
Tension build-up in cells and in biomimetic systems
Cell tension plays a crucial role in many biological processes; in particular, acto-myosin cortical tension drives many events of cell fate, including cell division. The tension of a cell is defined by analogy with the surface tension of a l(...)
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Volker Bormuth (LJP, UPMC). ENS-ESPCI Biophysics Seminar
Whole-brain imaging during vestibular stimulation in zebrafish with a novel rotatable light-sheet microscope
Light-sheet microscopy allows cell resolved whole-brain calcium imaging at several brain scans per second in zebrafish larvae. Currently this technique is not compatible with dynamic (...)
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François Robin (IPBS, UPMC, Paris). ENS-ESPCI Biophysics Seminar
Organizing embryonic contractility in space and time.
Actomyosin dynamics in morphogenesis, from tissue to single molecules
The mechanical properties of embryonic cells define the landscape that drives morphogenesis. These mechanical properties deri(...)
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Patricia Davidson (Institut Curie, Paris). ENS-ESPCI Biophysics Seminar
LINC-ing the cell nucleus, mechanics and disease
The ability of cells to migrate through tissues and interstitial spaces is essential during development and tissue homeostasis, immune cell mobility, and in various human diseases. In particular, deformation of the nucleus a(...)
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Rachid Thiam (LPS, ENS, Paris). ENS-ESPCI Biophysics Seminar
Biogenesis mechanism of fat storage organelles
All organisms are able to store excess energy in order to buffer energy fluctuations. Excess energy is stored in the form of neutral lipids, i.e. fat, encapsulated in organelles called lipid droplets. These droplets are at the core of cellular l(...)
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Gregory Batt (INRIA, Saclay). Biophysics seminar ESPCI-ENS.
Balancing a genetic toggle switch by real-time control or periodic stimulations
The ability to routinely control complex genetic circuits in vivo and in real-time promises quantitative understanding of cellular processes of unprecedented precision, quality, and richness. W(...)
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Juliette Azimzadeh (Institut Jacques Monod). Biophysics seminar ESPCI-ENS.
Identification of Conserved Centriole Components Controlling Centriole Rotational Polarity in Multiciliated Cells
Multiciliated cells form hundreds of motile cilia that beat in a coordinated fashion to generate a fluid flow or displace particles and cells. To generate a directional fluid flow(...)
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Anton Zadorin (ESPCI, Paris). Biophysics seminar ESPCI-ENS.
Synthesis of a reaction-diffusion French flag pattern
A central question of morphogenesis is the unfolding of genetic information into successive steps of complexification of an initially relatively simple egg or a bud. Experiments show that very often cellular differentia(...)
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Francis Corson (LPS, ENS). Biophysics seminar ESPCI-ENS.
Positional information and self-organization: how the fly lays out its sense organs
The emergence of spatial patterns in developing multicellular organisms relies on positional cues and cell-cell communication. Drosophila sensory organs have informed a paradigm where these(...)
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César Valencia-Gallardo (Collège de France). Biophysics seminar ESPCI-ENS.
Title and abstract to be anounced
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Pierre-Yves Colin (UCL, UK). Biophysics seminar ESPCI-ENS.
Title and abstract to be anounced
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Serge Dmitrieff (EMBL). Biophysics Seminar ESPCI-ENS.
Balance of microtubule stiffness and cortical tension determines the size of blood cells with marginal band across species
The fast blood stream of animals is associated with large shear stresses. Consequently, blood cells have evolved a special morphology and internal architecture allowing t(...)
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Quantitative biology on cells using microfluidic arrays. Charles Baroud (Polytechnique & Institut Pasteur). Biophysics Seminar ESPCI-ENS.
Quantitative measurements on single cells are typically performed through flow cytometry, which yields high throughput data but only at a single instant on individualised cells. This leaves many unmet needs, such as following cell fate in time, looking at interactions between cells, or relating the cell behavior wit(...)
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Amaury Lambert (Collège de France). Biophysics Seminar ESPCI-ENS
Chromosome painting
This talk is about a simple mathematical model of neutral population genetics with recombination. We assume that at time 0, all individuals of a haploid population have their unique chromosome painted in a distinct color. Now at each birth event, the chromosome of the newb(...)
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Anton Crombach (CIRB, College de France). Biophysics Seminar ESPCI-ENS.
Quantitative mechanisms explain system drift in the dipteran gap gene network
Dipterans (flies, midges, and mosquitoes) determine segmentation along their main body axis during the blastoderm stage of embryogenesis. In the initial phase of segmentation, maternal gr(...)
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Maxime Deforet (Memorial Sloan Kettering Cancer Center, New York). Biophysics Seminar ESPCI-ENS.
Bacterial swarming, an experimental model for studying morphogenesis and evolution in expanding populations
Bacterial swarming is the ability to collectively spread across surfaces. In Pseudomonas aeruginosa, an opportunistic pathogen, swarming colonies exhibit str(...)
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Jean Leon Maitre (GDB, Institut Curie). Biophysics Seminar ESPCI-ENS
Mechanics of blastocyst morphogenesis
During pre-implantation development, the mammalian embryos forms the blastocyst, the structure that will implant into the uterus. Consisting of an epithelium enveloping a fluid-filled cavity and the inner cell mass, the blastocyst is s(...)
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Andrea Perez-Villa (IMPMC, UPMC, Paris). Biophysics Seminar ESPCI-ENS
Title and abstract to be announced
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Nicholas Rossi (University of Vermont). Biophysics seminar ESPCI-ENS
How master regulators coordinate antibiotic resistance without sacrificing downstream specialization
Stress response networks frequently have a single upstream regulator that controls many downstream genes. However, the downstream targets are often diverse, therefore it remains unclear how th(...)
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Armita Nourmohammad (Princeton University). Biophysics Seminar ESPCI-ENS.
Statistical Physics of molecular evolution: from gene regulation to immune system.
Molecular phenotypes, such as gene expression or protein binding affinities are important targets of natural selection, and are often subject to time-dependent pressure form the env(...)
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Biophysics seminar : Edo Kussell (NYU)
Evolutionary phase transitions in random environments
Bacteria can use memory mechanisms to increase long term growth rates in rapidly changing environments. In this talk, I will discuss experiments that show the existence of phenotypic memory in E.coli during metabolic tr(...)
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Séminaire de Biophysique ENS-ESPCI. Olivier Tenaillon (Faculté de Médecine Xavier Bichat).
"Mutational Landscape of Betalactamase TEM-1"
Adaptation proceeds through the selection of mutations. The distribution of mutant fitness effect and the forces shaping this distribution are therefore keys to predict the evolutionary fate of organisms and their constituents such as enzymes. Here, by producing a(...)
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Nacho Molina (IGBM, Strasbourg). ENS-ESPCI Biophysics Seminar